Selected Publications

Propionate metabolism is dysregulated in non-small cell lung cancer patients and EGFR-mutant drug-tolerant persister cells.

Parang B, Yoffe L, Khan R, Li Z, Nagiec MJ, Gardner EE, Shieh Y, Heise RS, Saxena A, Altorki N, Blenis J. Sci Rep. 2026 Mar 18. doi: 10.1038/s41598-026-44451-2

The impact of preoperative imaging strategies in EGFR-mutant non-small cell lung cancer: a multicenter retrospective review.

Lee JW, Rafizadeh M, Bogdan S, Altorki N, Garcia C, Saxena A, Parang B.

medRxiv [Preprint]. 2025 Nov 2:2025.10.30.25339077. doi: 10.1101/2025.10.30.25339077.

Second-line therapy following osimertinib in metastatic EGFR-mutated non-small cell lung cancer at an academic medical center.

Rafizadeh M, Bogdan S, Lee J, Garcia C, Saxena A, Zhou K, Parang B.

medRxiv [Preprint]. 2025 Oct 31:2025.10.29.25339070. doi: 10.1101/2025.10.29.25339070.

Lysosome-dependent nutrient scavenging underlies stress adaptation during epithelial-to-mesenchymal transition.

Nagiec MJ, Cavaliere PM, Dundar F, Spencer DM, Koundouros N, Nunes JB, Shin S, Yoon SO, Han J, Chavez A, Kester OM, Khan R, Zumbo P, Gardner EE, Parang B, Mutvei AP, Asara JM, Gygi SP, Betel D, Dephoure N, Blenis J.

bioRxiv [Preprint]. 2025 Sep 23:2025.09.22.677807. doi: 10.1101/2025.09.22.677807.

Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling.

Koundouros N, Nagiec MJ, Bullen N, Noch EK, Burgos-Barragan G, Li Z, He L, Cho S, Parang B, Leone D, Andreopoulou E, Blenis J.

Science. 2025 Mar 14;387(6739):eadm9805. doi: 10.1126/science.adm9805. Epub 2025 Mar 14.

PMID: 40080571

MTGR1 is required to maintain small intestinal stem cell populations.

Short SP, Brown RE, Chen Z, Pilat JM, McElligott BA, Meenderink LM, Bickart AC, Blunt KM, Jacobse J, Wang J, Simmons AJ, Xu Y, Yang Y, Parang B, Choksi YA, Goettel JA, Lau KS, Hiebert SW, Williams CS.

Cell Death Differ. 2024 Sep;31(9):1170-1183. doi: 10.1038/s41418-024-01346-x. Epub 2024 Jul 25.

PMID: 39048708 Free PMC article.

Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.

Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, Cantley LC, Laughney AM, Blenis J.

Nat Commun. 2022 Oct 20;13(1):6239. doi: 10.1038/s41467-022-33862-0.

Blood vessel epicardial substance reduces LRP6 receptor and cytoplasmic β-catenin levels to modulate Wnt signaling and intestinal homeostasis.

Thompson JJ, Short SP, Parang B, Brown RE, Li C, Ng VH, Saito-Diaz K, Choksi YA, Washington MK, Smith JJ, Fingleton B, Brand T, Lee E, Coffey RJ, Williams CS.

Carcinogenesis. 2019 Sep 18;40(9):1086-1098. doi: 10.1093/carcin/bgz007.

BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.

Parang B, Kaz AM, Barrett CW, Short SP, Ning W, Keating CE, Mittal MK, Naik RD, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Brand T, Bader DM, Tansey WP, Chen R, Brentnall TA, Grady WM, Williams CS.

Gut. 2017 May;66(5):852-862. doi: 10.1136/gutjnl-2015-310255. Epub 2016 Jan 14.

Myeloid translocation genes differentially regulate colorectal cancer programs.

Parang B, Bradley AM, Mittal MK, Short SP, Thompson JJ, Barrett CW, Naik RD, Bilotta AJ, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Hiebert SW, Williams CS.

Oncogene. 2016 Dec 8;35(49):6341-6349. doi: 10.1038/onc.2016.167. Epub 2016 Jun 6.

A workshop on leadership for senior MD-PhD students.

Meador CB, Parang B, Musser MA, Haliyur R, Owens DA, Dermody TS.

Med Educ Online. 2016 Aug 5;21:31534. doi: 10.3402/meo.v21.31534. eCollection 2016.

The transcriptional corepressor MTGR1 regulates intestinal secretory lineage allocation.

Parang B, Rosenblatt D, Williams AD, Washington MK, Revetta F, Short SP, Reddy VK, Hunt A, Shroyer NF, Engel ME, Hiebert SW, Williams CS.

FASEB J. 2015 Mar;29(3):786-95. doi: 10.1096/fj.14-254284. Epub 2014 Nov 14.